Nanoparticle Carriers
Lipid Nanoparticle Formulation Variables and Peptide Encapsulation Efficiency
Peptide cargo requires different lipid formulation rules than the mRNA vaccines that came before.
Tobias Mehring
· 10 min read
Route of Administration — Page 2
CSF Pharmacokinetics and Brain Parenchyma Drug Distribution
CSF presence doesn't guarantee drug reaches the brain tissue where it needs to work.
Tobias Mehring
GLP-1 Receptor Agonists and Neurodegeneration Research
Brain receptors built for blood sugar control may slow Alzheimer's and Parkinson's decline.
Séverine Okafor
GLP-1 Receptor Distribution in the Human Brain
Brain GLP-1 receptors cluster in cortex, not cerebellum, unlike rodents.
Tobias Mehring
Focused Ultrasound for Transient Blood-Brain Barrier Opening
Ultrasound and microbubbles open the brain to drugs without invasive surgery.
Séverine Okafor
Intranasal GLP-1 Delivery for Addiction and Reward Circuit Modulation
Intranasal delivery bypasses the blood-brain barrier to reach addiction's core neural circuits.
Tobias Mehring
Biotech Companies Developing Nose-to-Brain Nanoparticle Platforms for CNS Indications
Nanoparticles engineered to bypass the blood-brain barrier through nasal delivery.
Marcus Tully-Byrne
Receptor-Mediated Transcytosis Across the Blood-Brain Barrier
Smart receptor-binding tricks unlock the brain's hidden import doors.
Tobias Mehring