Volume of Distribution and CNS Penetration for Therapeutic Peptides
Large peripheral distribution doesn't guarantee brain access for therapeutic peptides.
Priya Venkatesan
Senior Science Correspondent
Priya Venkatesan spent a decade as a formulation scientist at a mid-size biotech before transitioning to science journalism in 2014, and now covers the technical and regulatory dimensions of intranasal and mucosal drug delivery. Her reporting draws heavily on primary literature and bench-side interviews with formulators and clinicians.
2 stories
Large peripheral distribution doesn't guarantee brain access for therapeutic peptides.
Nasal delivery bypasses the blood-brain barrier through direct neural pathways.